Cannabis Post-Arthroplasty: Increased Risks Highlighted in 2023 Meta-Analysis

Introduction
The meta-analysis by Turan et al. (J Arthroplasty, Feb 2024, published July 2023) examines the relationship between cannabis use and outcomes following total joint arthroplasty (TJA). With the growing legalization of cannabis, understanding its perioperative implications is crucial for orthopedic surgeons and perioperative teams.

Key Findings

  1. Elevated Postoperative Risks: Cannabis use is linked to higher incidences of surgical site infections and delayed wound healing, consistent with its known effects on vascular and immune function.
  2. Possible Mechanisms: THC and cannabinoids may interfere with pharmacodynamics of antibiotics and other post-surgical medications. Additionally, cannabis’s effects on platelet aggregation and inflammatory response could explain delayed recovery.
  3. Implications for Patient Care: Routine preoperative screening for cannabis use could be an essential addition to risk stratification protocols, especially in high-risk patients. Educating patients about these risks preoperatively could also improve outcomes.

Summary: The VitalPoint for Providers
This study reinforces the need for clinicians to discuss cannabis use with TJA candidates as part of comprehensive preoperative planning. Incorporating this knowledge into patient management strategies will enhance surgical outcomes and reduce postoperative risks.
Access the study at PubMed.

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